Other names: Tofranil
Non branded versions available.
Imipramine is an antidepressant. In multiple sclerosis, and other conditions, a low dose may be used for pain relief, particularly for neuropathic pain in the arms and legs, eg burning sensations, pins and needles or stabbing pains. It can also be used for some mild bladder symptoms.
What is imipramine used for in MS?
Who can take imipramine?
If you are pregnant or breastfeeding talk to your doctor before taking imipramine.
If you have a history of heart disease or glaucoma, a problem with the eye, talk to your doctor before starting treatment
How do I take imipramine?
Amitriptyline is taken by mouth (orally) as tablets.
What side effects could I get with imipramine?
Side effects include feeling drowsy, dry mouth, blurred vision, headache and increased appetite. Some side effects may ease off over time.
How does imipramine work?
Imipramine is one of a class of drugs called tricyclic antidepressants. These change the balance of chemicals in the brain that pass messages between nerves. This alters the way in which the central nervous system reacts to pain. Imipramine also affects the rate at which urine is produced.
Last reviewed: April 2016
This page will be reviewed within three years