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Primary progressive MS exposed Trials in primary progressive MS

Historically, primary progressive MS has been the least studied of the different clinical types of MS. The lack of trials, along with the fact that there is no treatment available that can modify the course of primary progressive MS, has understandably led to people feeling like they are on the periphery of research into new treatments, especially when compared to those with relapsing remitting MS. However, the situation has slowly begun to improve in the last decade since both the definition of primary progressive MS and the diagnostic criteria have been tightened. The increase in the amount of research being carried out, along with more information being produced that is tailored specifically for people with primary progressive MS, should in time help overcome the perception of being the 'forgotten few'.

Challenges to trials
Past and current trials
Questions still to be answered
Future research priorities