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MS research update - How common is stress urinary incontinence in women with MS? - 02 August 2012

Stress urinary incontinence is losing urine without meaning to during physical activity, such as coughing, sneezing, laughing, or exercise. It occurs in the general population especially after childbirth and is more common with increasing age or obesity. It affects more women than men.

Urgency urinary incontinence is when someone has a desperate urge to go to the toilet with little or no warning.

People with MS are at higher risk of urinary incontinence because of damage to the nerves controlling the bladder. This study used a questionnaire to ask women with MS, who were attending outpatient follow up appointments at an MS centre, about stress urinary incontinence and urgency urinary incontinence. They also investigated how much these symptoms made an impact on their quality of life especially when undertaking physical activity. The participants ranged in age from 20 to 72 (the average age was 46).

They found that over half (56%) experienced stress incontinence, almost three quarters (71%) had urgency incontinence and many (45%) had both. Women with stress incontinence were generally older and had a greater body mass index, indicating a greater proportion of body fat.

Women with stress incontinence reported a significant impact on their ability to do physical activity. The researchers suggest that urologic assessment of women with MS should include an assessment of stress incontinence.

Murphy AM, Bethoux F, Stough D, et al.
Prevalence of stress urinary incontinence in women with multiple sclerosis.
Int Neurourol J. 2012 Jun;16(2):86-90.

You can read about managing bladder problems in the A-Z of MS and order or download the book: Managing your bladder

Research by topic areas...

Symptoms and symptom management

Naderi F, Javadi SA, Motamedi M, et al.
The efficacy of primidone in reducing severe cerebellar tremors in patients with multiple sclerosis.
Clin Neuropharmacol. 2012 Jul 19. [Epub ahead of print]

Pollock BE, Stein KJ.
Outcomes after microvascular decompression for patients with trigeminal neuralgia and suspected multiple sclerosis.
Neurosurgery. 2012 Aug;71(2):E577.

Mohammadi AM, Lee JH, Barnett GH.
Surgical outcomes of trigeminal neuralgia in patients with multiple sclerosis.
Neurosurgery. 2012 Aug;71(2):E563-4.

Montano N, Papacci F, Cioni B, et al.
What is the best treatment of drug-resistant trigeminal neuralgia in patients affected by multiple sclerosis? A literature analysis of surgical procedures.
Clin Neurol Neurosurg. 2012 Jul 26. [Epub ahead of print]


Ford DV, Jones KH, Middleton RM, et al.
The feasibility of collecting information from people with multiple sclerosis for the UK MS Register via a web portal: characterising a cohort of people with MS.
BMC Med Inform Decis Mak. 2012 Jul 18;12(1):73. [Epub ahead of print]

Assessment tools

Motl RW, Balantrapu S, Pilutti L, et al.
Symptomatic correlates of six-minute walk performance in persons with multiple sclerosis.
Eur J Phys Rehabil Med. 2012 Jul 23. [Epub ahead of print]

Psychological aspects

Hardmeier M, Schoonheim MM, Geurts JJ, et al.
Cognitive dysfunction in early multiple sclerosis: altered centrality derived from resting-state functional connectivity using magneto-encephalography.
PLoS One. 2012;7(7):e42087.

Physical activity

Motl RW, Pilutti L.
The benefits of exercise training in multiple sclerosis.
Nat Rev Neurol. 2012 Jul 24. doi: 10.1038/nrneurol.2012.136.[Epub ahead of print]

Huisinga JM, Yentes JM, Filipi ML, et al.
Postural control strategy during standing is altered in patients with multiple sclerosis.
Neurosci Lett. 2012 Jul 21. [Epub ahead of print]

Giacobbi PR Jr, Dietrich F, Larson R, et al.
Exercise and quality of life in women with multiple sclerosis.
Adapt Phys Activ Q. 2012 Jul;29(3):224-42.


Zoccolella S, Tortorella C, Iaffaldano P, et al.
Low serum urate levels are associated to female gender in multiple sclerosis patients.
PLoS One. 2012;7(7):e40608.

Pregnancy and childbirth

Coyle PK.
Pregnancy and multiple sclerosis.
Neurol Clin. 2012 Aug;30(3):877-88.

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