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Other name: Neurontin. Several non branded versions are available.

What is gabapentin used for in MS?

Gabapentin is a drug used in the treatment of neuropathic pain in multiple sclerosis, that is pain caused directly by the effects of MS, such as trigeminal neuralgia or abnormal sensations (dysaesthesia), such as burning or pins and needles. The NICE Guideline recommends gabapentin as one of the first drugs to try in the treatment of spasms and spasticity.

How do I take gabapentin?

Gabapentin is taken orally as tablets. When stopping treatment, the dosage should be gradually reduced.

What side effects could I get with gabapentin?

Side effects can include sedation, dizziness, fatigue and weakness.

How does gabapentin work?

Gabapentin is an anticonvulsant and anti-epileptic drug.


  • Cutter NC, et al. Gabapentin effect on spasticity in multiple sclerosis: a placebo-controlled, randomized trial. Archives of Physical Medicine & Rehabilitation 2000;81(2):164-169. Summary
  • Mellegers M, et al. Gabapentin for neuropathic pain: systematic review of controlled and uncontrolled literature. Clinical Journal of Pain 2001;17:284-295. Summary

Last updated: 5 November 2014
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