In the event of this happening and in the interest of people with MS the MS Trust will seek confirmation from the organisation or individual that the study has the appropriate ethical approval and that any information or advert that we are being asked to share with you has ethical approval. In addition we will ensure that contact details are obtained should further information be required.
This is the only action that the MS Trust will take and we assume no further responsibility for the information shown.
Please note if you do require any further information about items posted here please use the contact details provided. The MS Trust has no further information and should not be contacted.
Can daily consumption of cocoa reduce fatigue in relapsing remitting MS?
A healthy diet may be a simple, cost effective and safe therapy for improving symptoms experienced in people with MS (pwMS), and thus for increasing quality of life. There is currently no cure for fatigue yet it is one of the most debilitating of symptoms associated with MS.
Pure cocoa may have the ability to improve fatigue due to compounds in the cocoa called flavonoids. However to date, no well-designed studies have looked at the role of cocoa consumption for fatigue management in pwMS.
This study will collect data comparing the effect of a high flavonoid pure cocoa drink to a low flavonoid cocoa drink on fatigue and blood levels of inflammatory markers in pwMS.
If you decide to participate in this study, you will be asked to attend 3 research visits over a 6 week period at Oxford Brookes, where we will measure your fatigue levels, take some blood samples (venous and finger prick samples, no more than 50 mls at each assessment) and ask you a series of questions about your daily life.
Each visit will last no more than 1 and half hours and they will take place before 10 am. If you agree to take part, you will first receive a phone call from the lead researcher in order to check that you are suitable for the trial.
At each visit you will be asked to:
- Recall your diet from the previous day, performed by a trained nutritionist;
- Walk for 6 minutes whilst being timed on a stopwatch to look at your mobility (1st and 3rd visit only). During this we would place a small device on your back that measures how you walk;
- Complete a few short questionnaires about your health and well-being;
- Have blood samples taken
At the final visit we will also ask you to answer some questions about your experiences of the study.
There may, or may not be, direct benefits to anyone taking part in this study. The study is being undertaken to find out whether certain dietary interventions are beneficial to pwMS. By taking part, you will be helping us to answer this question, which may be of benefit to pwMS in the future.
Lead researcher Dr Shelly Coe, firstname.lastname@example.org
Tel 01865 483839
Cognitive rehabilitation for attention and memory in people with MS
The CRAMMS (Cognitive rehabilitation for attention and memory in people with MS) trial is designed to test whether a ten session group memory rehabilitation programme improves memory and reduces problems with memory in everyday life.
The study is being co-ordinated by researchers from the University of Nottingham.
The treatment is taking place in four centres in Nottingham, Liverpool, Sheffield and Bristol, and recruiting participants from their surrounding areas. There are also plans to recruit from the Middlesbrough area later in 2016.
There is more information on the study website for people who have memory problems and are interested in taking part.
For more information e-mail email@example.com or phone 0115 8231615.
How people living with MS search for medical information online
A PhD research student from Swansea University Medical School is looking for participants to take part in a survey study that aims to explore how people living with MS search for medical information online.
Participants will be asked to complete an online questionnaire exploring the following questions:
- How people with MS determine the quality of the information they find on websites?
- What types of information they usually view online with regards of MS medicines related information?
- Would the availability of an online resource help people with MS to make informed treatment choices (e.g. side effects of prescribed medications)?
Participants will be asked to complete an online questionnaire. Anyone over the age of 18 with a confirmed diagnosis of MS or a person who provides care for someone with MS can take part.
If you would like to find out more about this study, please contact Adel Alhlayl or any of the supervisors of this project. Dr Gareth Noble, Dr Melanie Healy , and Dr Kerina Jones.
If you would like to participate in the survey, please read the our study information sheet.
Women's sources of information, knowledge and use of continence products
Urinary incontinence is a major health problem, which for many women requires the use of continence products or pads. Not a lot is known about how women gather knowledge about continence products.
If you are a woman over the age of 30 that uses some sort of continence products to mange your bladder weaknesses please can you take this survey. It will take no longer than 10 minutes to complete.
For futher information, visit the website explaining the survey or contact Nicholas Smith on +1 780 492 6855
Understanding self-management in MS
A PhD research student from University College London Interaction Centre is looking for participants to take part in a study that aims to explore the ways that people living with MS manage their health and how they could help to support self-management with valuable technologies.
Participants will be asked to take part in an interview study exploring the following questions:
• In what ways do people use different tools to manage their health (e.g. paper diaries, spreadsheet software, websites, mobile apps, fitness tracking devices, etc.)?
• What do they track (e.g. physical activity, mood, pain, fatigue, diet, etc.)?
• What kind of challenges do they face and what do they learn?
Anyone over the age of 18 with a confirmed diagnosis of MS can take part, and they are interested in speaking to people with may have used any tools to track their health condition, though this is not essential.
The interview can be conducted in person, via phone or Skype. As a thank you for taking part you will receive a £20 Amazon voucher.
If you would like to find out more about this study and would like to receive a participant information sheet, please contact Amid , who is a PhD research student at the University College London Interaction Centre.
Study advert (PDF, 37KB)
The MS-SMART study is a clinical trial for people with a diagnosis of secondary progressive MS that will look at drugs that may limit the progression of MS.
The trial will involve three drugs that are currently licensed for other conditions:
- fluoxetine for treating depression
- riluzole for motor neurone disease
- amiloride for high blood pressure and heart disease
Studying drugs where the safety profile is already known potentially shaves years off the time usually needed to test newly-developed treatments. Previous studies have suggested that these drugs might be neuroprotective - protecting nerves from further damage from MS.
Participants will take one of the drugs or placebo for two years, but no one will know which treatment they are taking while the trial is on-going.
There are study centres across the UK, but the researchers are in particular need for more participants in the London area.
For further details about the study, visit the MS-Smart website which lists the hospitals involved in the study, more details on taking part and the opportunity to express an interest in participating.
You can also email Dr Domenico Plantone at UCL, Institute of Neurology, Queen Square, London or telephone 07572898453.
Understanding depression and anxiety in people living with multiple sclerosis
Investigators at Liverpool University are conducting research to help understand more about emotional distress in MS. They are interested in how people make sense of their illness and the nature of depression and anxiety in MS. It is possible that some people will have experienced depression and anxiety during the course of their illness, whereas others may never have experienced these difficulties. It is important to get a sense of different perspectives to build a more complete understanding of the psychological aspects of depression and anxiety in people living with MS.
People with a diagnosis of MS are invited to take part in this study people regardless of how they currently feel to get a broad picture of depression and anxiety in people living with the condition.
You will be asked to complete a set of online questionnaires (taking approximately 30 minutes) at the beginning of the study and again about 12 weeks later.
To thank participants for taking part in the study the investigators are offering the chance to enter a prize draw for one of three £50 gift vouchers. Details will be given at the end of the study to those that have completed the surveys.
If you are interested in taking part, or would like to hear more about the study, please email Phillip Heffer-Rahn. Information about the study and a consent form will also be presented before the survey begins.
Study advert (PDF 17 KB)
Participation information sheet (PDF 53 KB)
Benefits and risks information for multiple sclerosis (BRIMMS)
Information about the risks and benefits of MS medication is becoming increasingly complex.
Researchers at Royal Holloway, University of London are designing a protocol to present risk and benefit information about MS medications in a way that is most helpful and accessible for people with MS.
If you would like to help, please fill in their anonymous online survey about your experiences and preferences relating to MS medication information.
Please feel free to pass this link on to any other people with MS whom you think may be interested.
For more information please email Miss Gurpreet Reen
UK MS Register
If you are over the age of 18 and living in the UK, with a confirmed diagnosis of multiple sclerosis made by a consultant neurologist, you are eligible to take part in this ground breaking study.
The UK MS Register is an online research project that hosts a variety of questionnaires that ask about YOU and YOUR MS to help researchers build a bigger picture of MS in the UK from the comfort of your own home.
With over 100,000 people living with MS in the UK, it's time we increased our knowledge and understanding. MS Register researchers are working to find out more about MS and the impact it has on the lives of those it affects.
By joining the community of people in the UK affected by MS and contributing to the MS Register, you will be directly involved in generating new research. The knowledge we gain from this study will fuel campaigns for fair, relevant policy and improved healthcare for people living with MS.
The MS Register is a ground-breaking study designed to increase our understanding of living with MS in the UK. Join the study by completing a series of simple questionnaires.
For more information please email UK MS Register or phone 01792 606354.
A study of lesbian, gay, bisexual and transsexual (LGBT) people living with MS
A researcher at De Montfort University in Leicester is investigating the experience of LGBT individuals living with MS. Lesbian, gay, bisexual, trans or a queer (LGBT) people diagnosed with multiple sclerosis who are over 18 years old are invited to take part in this study.
Usually when LGBT health has been researched there has been a focus on sexual and mental health rather than physical health in general. LGBT people's experiences of chronic illness (including MS), other than HIV, have not been investigated. The purpose of this study is to explore lesbian, gay, bisexual, trans and queer individuals' experiences of living with multiple sclerosis.
"Your participation will happen in two levels. I will ask you to take as many photos as you like (with a personal camera, smartphone or any other equipment you find suitable) during a two weeks period. If you prefer I can provide you with a disposable camera. The photos will have to be related to your experience as an LGBT person with MS. Please note you will not be expected to pay for any element of developing the photographs. Then you will be asked to bring with you 5-10 photos (either printed or in a digital form) of your choosing in an interview which we will arrange together, immediately after the two weeks period. It's up to you where you want the interview to take place (e.g. personal residence, DMU premises or venue of your choosing). Alternatively, there is the option of an interview via Skype if there are issues of distance."
Participant information sheet (PDF 453 KB)
For more information please email Periklis Papaloukas or phone 07873 930955.
Abdominal massage for bowel problems
A team at the Nursing, Midwifery and Allied Professional Health Unit (Glasgow Caledonian University and Stirling University) are looking at whether the use of abdominal massage can improve symptoms of bowel problems in people with MS.
The study will take place at study centres across the UK. Participants attend an initial appointment with a trained nurse and are allocated to either intervention group (optimised bowel care and abdominal massage training) or control group (optimised bowel care only). Participants then complete weekly bowel diaries and follow-up calls with nurses at home for up to 6 weeks and again at 24 weeks after the initial appointment. There is also an opportunity for those in the group doing abdominal massage to take part in a telephone interview sub-study.
For more information please email AMBER@gcu.ac.uk or telephone the Trial Office on 0141 331 3516.
Fatigue in childhood MS
A PhD student at Kings College London is looking for participants to take part in a study investigating the impact of fatigue on young people with MS.
Children and adolescents (aged 18 years or younger) who have MS and experience fatigue as a symptom are invited to take part. Primary caregivers of children and adolescents with MS and fatigue can take part too.
Participants will take part in a 30-60 minute interview with a member of the research team; children and caregivers will be interviewed separately.
Each participant will receive a £10 shopping voucher as a thank you for taking part.
If you are interested in taking part, or would like to hear more about the study, please email Susan Carroll or phone Susan on 020 7188 0196).
Study advert(PDF 72.7KB)
Information Sheet for Children (age 6-12) (PDF 283 KB)
Information Sheet for Teens (age 13-15) (PDF 363 KB)
Information Sheet for Adolescents (age 16+) (PDF 339 KB)
Information Sheet for Primary Caregivers (PDF 343 KB)
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