A to Z of MS Nystagmus
This is a condition in which the eyes are seen to move in a more or less rhythmical manner, from side to side, up and down, or in a rotary manner from the original point of fixation. This sometimes goes unnoticed by the person with MS but is clearly seen by the observer. If it more persistent, nystagmus may contribute to dizziness or nausea.
Nystagmus can be a difficult symptom to treat. Occasionally drug therapy can help. NICE Guideline for management of MS states that "any person who has nystagmus that causes reduced visual acuity or other visual symptoms should be offered a time-limited trial of treatment with oral gabapentin. This should be initiated and monitored by a suitable specialist".
A small study also suggest that memantine is also effective and very recently the use of a muscle relaxant injection (botulinum) into the eye muscles can show benefit.
Reference
Shery T, et al.
The effects of gabapentin and memantine in acquired and congenital nystagmus: a retrospective study.
British Journal of Ophthalmology 2006;90(7):839-843.
abstract

