A to Z of MS Oxybutynin
Product names
Ditropan, Lyrinel XL
Oxybutynin is an anticholinergic drug that is used to improve bladder storage capacity. It is used in the treatment of urinary frequency and urgency.
How oxybutynin works
All anticholinergic drugs reduce the action of the chemical messenger that passes nerve messages to the muscle in the bladder wall. This reduces the bladder's tendency to contract. The same chemical messenger activates the salivary glands, and as oxybutynin suppresses these, dry mouth is a common side effect of the medication.
How is oxybutynin given
Oxybutynin is taken orally as tablets. Starting dose may be 2.5mg twice daily, or 5mg once a day in one tablet. The dose should not exceed 5mg three times a day.
Side effects and contraindications
Dry mouth is the main side effect. Pregnant and breastfeeding women should seek a doctor's advice.
All anticholinergic drugs may worsen urinary retention so monitoring how much urine is retained in the bladder before starting on medication is important.