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A to Z of MS Immunisation and vaccination

In the past there has been concern over the potential effect of vaccinations on people with MS. Research has failed to find evidence to support these concerns. A study in France published in 2001 compared the relapse history of 643 people with MS with their vaccinations against tetanus, hepatitis B or influenza. The study found no evidence that vaccination increased the short-term risk of a relapse.

The NICE Guideline states that there is no reason why people with MS should not have all the vaccinations that are required both for use in the UK and when travelling abroad. It is preferable to be protected than run the risk of contracting the diseases, many of which are serious and life threatening.

There are a few exceptionally rare complications of the vaccinations themselves but the risk of these occurring are the same for people with MS as in the general population.

Exceptions

  • People who are experiencing a debilitating relapse may be advised to defer vaccination.
  • People on therapies that suppress the immune system, such as mitoxantrone, azathioprine, methotrexate, cyclophosphamide or steroids should not receive certain vaccines as they may be at greater risk for developing the disease. Make sure that your doctor is aware of all the medications you are taking.

Reference

Confavreux C, et al.
Vaccinations and the risk of relapse in multiple sclerosis. Vaccines in Multiple Sclerosis Study Group.
New England Journal of Medicine 2001;344(5):319-326.
abstract

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