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In multiple sclerosis, lesion, or plaque, refers to an area of damage or scarring (sclerosis) in the central nervous system caused by MS. On MRI scans lesions show up as white patches.

Lesions are caused by inflammation that results from the immune system attacking the myelin sheath around nerves. Lesions are associated with damage to myelin and potentially the destruction of nerve axons.

Last updated: 28 March 2014
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